Apolipoprotein B

Apolipoprotein B (APOB) is the primary apolipoprotein of low density lipoproteins (LDL),  or “bad cholesterol”, which is responsible for carrying cholesterol to tissues.  APOB “unlocks” the doors to cells and thereby delivers cholesterol to them.

High levels of APOB can lead to plaques that cause heart disease.

Recent research shows that levels of APOB are a better indicator of heart disease risk than total cholesterol or LDL.

Transgenic mice that overexpress mouse apolipoprotein B. Evidence that the DNA sequences controlling intestinal expression of the apolipoprotein B gene are distant from the structural gene. J Biol Chem. 1996 May 17; 271(20): 11963-70; Knockout of the Mouse Apolipoprotein B Gene Results in Embryonic Lethality in Homozygotes and Protection Against Diet-Induced Hypercholesterolemia in Heterozygotes. Proc Natl Acad Sci USA. 1995 Feb 28; 92(5): 1774-8;

About The Author

Kelley Herring, founder of Healing Gourmet, is a natural nutrition enthusiast with a background in biochemistry. Her passion is educating on how foods promote health and protect against disease and creating simple and delicious recipes for vibrant health and enjoyment.

Kelley Herring – who has written posts on Healing Gourmet.

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